Bioassay of Pesticide Lindane Using Yeast-DNA Microarray Technology
نویسندگان
چکیده
منابع مشابه
Bioassay of lindane for possible carcinogenicity.
A bioassay for possible carcinogenicity of lindane was conducted by administering the test chemical in the diet to Osborne-Mendel rats and B6C3F1 mice. Groups of 50 rats of each sex were administered lindane at one of two doses for 80 weeks, then observed for 29-30 weeks. Time-weighted average doses for males were 236 or 472 ppm; those for females were 135 or 270 ppm. Matched controls consisted...
متن کاملToxicity of organochlorine pesticide, Lindane to fish: A review
Lindane, an organochlorine pesticide, has been widely used in public health and agriculture in several countries including India. Lindane has long been associated with pollution due to its long persistence and quick accumulation in fatty tissues. It is considered a possible carcinogen, mutagen, teratogen, immunotoxin, and neurotoxin in mammals. However, data on toxicity of lindane to fish is in...
متن کاملDNA microarrays: boundless technology or bound by technology? Guidelines for studies using microarray technology.
The biotechnology revolution has led to unprecedented progress in elucidating the structure of the human genome and determining patterns of gene expression relevant to disease pathogenesis. Each new breakthrough produces an immediate and often intense flurry of activity as investigators explore its place in the scientific repertoire and determine the insights it provides for understanding disea...
متن کاملDNA microarray technology: devices, systems, and applications.
In this review, recent advances in DNA microarray technology and their applications are examined. The many varieties of DNA microarray or DNA chip devices and systems are described along with their methods for fabrication and their use. This includes both high-density microarrays for high-throughput screening applications and lower-density microarrays for various diagnostic applications. The me...
متن کاملGene expression profiling by DNA microarray technology.
Methods in molecular and genetic biology have provided important clues to elucidate the complex mechanisms of oral and craniofacial development and pathogenesis of diseases. It has become increasingly clear that a biological phenotype is a result of multiple factors involving a large number of regulatory genes, while a single nucleotide mutation can cause various degrees of oral and craniofacia...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chem-Bio Informatics Journal
سال: 2003
ISSN: 1347-0442,1347-6297
DOI: 10.1273/cbij.3.12